GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10461617 | 1 | rs252887 | chr5:56166188 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 9.04 | 1.84E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252898 | chr5:56188931 | C5orf35 | chr5:56205103-56213010:+ | 0.76 | 9.51 | 1.87E-15 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252902 | chr5:56116085 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 8.92 | 3.44E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252904 | chr5:56118733 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 8.98 | 2.55E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252909 | chr5:56121131 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 8.92 | 3.44E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252910 | chr5:56192983 | C5orf35 | chr5:56205103-56213010:+ | 0.77 | 9.52 | 1.72E-15 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252915 | chr5:56121754 | C5orf35 | chr5:56205103-56213010:+ | -0.74 | -8.92 | 3.44E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252916 | chr5:56121788 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 9.44 | 2.59E-15 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252919 | chr5:56124111 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 8.92 | 3.44E-14 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252921 | chr5:56137787 | C5orf35 | chr5:56205103-56213010:+ | 0.77 | 9.57 | 1.35E-15 | Type 2 diabetes |
| THYM | cis | rs10461617 | 1 | rs252922 | chr5:56136343 | C5orf35 | chr5:56205103-56213010:+ | 0.77 | 9.57 | 1.35E-15 | Type 2 diabetes |
| THYM | cis | rs2243480 | 1 | rs2533288 | chr7:66056711 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs7849270 | 1 | rs2541161 | chr9:131884802 | CRAT | chr9:131857075-131873070:- | -0.42 | -4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs2541164 | chr9:131876908 | CRAT | chr9:131857075-131873070:- | 0.47 | 5.4 | 4.92E-7 | Blood metabolite ratios |
| THYM | cis | rs10461617 | 1 | rs2548664 | chr5:56133555 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 8.92 | 3.44E-14 | Type 2 diabetes |